Rurouni Kenshin is set in the Meiji Era and follows a former assassin seeking redemption in Japan's turbulent times.
Samurai Champloo takes place in the Edo period. It's about two samurai on a hip-hop-inspired adventure with a young girl.
Dororo is another good option. This one is set in the Warring States era and follows a demon-hunting journey.
It takes place in Edo-era Japan and is about an immortal swordsman who helps a girl get revenge.
Shigurui: Death Frenzy is set in the Edo period as well. It focuses on a deadly tournament between samurai.
Basilisk has feudal Japan as its backdrop. The story revolves around ninja clans battling to serve the Shogun.
In Samurai: Hunt for the Sword, a samurai is on a quest to find a legendary sword in the Edo period.
Sengoku Basara depicts various samurai fighting for control of Japan in the Warring States period.
Final Fantasy VII follows the story of Cloud Strife and his allies as they fight against a new threat to the world.
Night Warriors: Darkstalkers features supernatural creatures battling for control.